WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID. The second row lists the following statistics:
Finally, genes in the gene set are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:Transcription Target       Name:hsa_V$ISRE_01       ID:DB_ID:2029
C=246; O=15; E=0.37; R=40.46; rawP=2.30e-20; adjP=1.27e-18
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000107201 NA DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 23586 ENSG00000107201
2  ENSG00000119922 NA IFIT2 interferon-induced protein with tetratricopeptide repeats 2 3433 ENSG00000119922
3  ENSG00000136514 NA RTP4 receptor (chemosensory) transporter protein 4 64108 ENSG00000136514
4  ENSG00000108771 NA DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 79132 ENSG00000108771
5  ENSG00000133106 NA EPSTI1 epithelial stromal interaction 1 (breast) 94240 ENSG00000133106
6  ENSG00000136040 NA PLXNC1 plexin C1 10154 ENSG00000136040
7  ENSG00000184979 NA USP18 ubiquitin specific peptidase 18 11274 ENSG00000184979
8  ENSG00000137965 NA IFI44 interferon-induced protein 44 10561 ENSG00000137965
9  ENSG00000130303 NA BST2 bone marrow stromal cell antigen 2 684 ENSG00000130303
10  ENSG00000213928 NA IRF9 interferon regulatory factor 9 10379 ENSG00000213928
11  ENSG00000119917 NA IFIT3 interferon-induced protein with tetratricopeptide repeats 3 3437 ENSG00000119917
12  ENSG00000115267 NA IFIH1 interferon induced with helicase C domain 1 64135 ENSG00000115267
13  ENSG00000137628 NA DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 55601 ENSG00000137628
14  ENSG00000132530 NA XAF1 XIAP associated factor 1 54739 ENSG00000132530
15  ENSG00000187608 NA ISG15 ISG15 ubiquitin-like modifier 9636 ENSG00000187608


Database:Transcription Target       Name:hsa_V$IRF_Q6       ID:DB_ID:2256
C=240; O=14; E=0.36; R=38.70; rawP=8.83e-19; adjP=2.43e-17
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000119922 NA IFIT2 interferon-induced protein with tetratricopeptide repeats 2 3433 ENSG00000119922
2  ENSG00000136514 NA RTP4 receptor (chemosensory) transporter protein 4 64108 ENSG00000136514
3  ENSG00000108771 NA DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 79132 ENSG00000108771
4  ENSG00000156587 NA UBE2L6 ubiquitin-conjugating enzyme E2L 6 9246 ENSG00000156587
5  ENSG00000059378 NA PARP12 poly (ADP-ribose) polymerase family, member 12 64761 ENSG00000059378
6  ENSG00000168961 NA LGALS9 lectin, galactoside-binding, soluble, 9 3965 ENSG00000168961
7  ENSG00000136040 NA PLXNC1 plexin C1 10154 ENSG00000136040
8  ENSG00000137965 NA IFI44 interferon-induced protein 44 10561 ENSG00000137965
9  ENSG00000130303 NA BST2 bone marrow stromal cell antigen 2 684 ENSG00000130303
10  ENSG00000213928 NA IRF9 interferon regulatory factor 9 10379 ENSG00000213928
11  ENSG00000068079 NA IFI35 interferon-induced protein 35 3430 ENSG00000068079
12  ENSG00000160710 NA ADAR adenosine deaminase, RNA-specific 103 ENSG00000160710
13  ENSG00000137628 NA DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 55601 ENSG00000137628
14  ENSG00000187608 NA ISG15 ISG15 ubiquitin-like modifier 9636 ENSG00000187608


Database:Transcription Target       Name:hsa_V$IRF7_01       ID:DB_ID:2110
C=250; O=13; E=0.38; R=34.50; rawP=7.66e-17; adjP=1.31e-15
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000107201 NA DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 23586 ENSG00000107201
2  ENSG00000119922 NA IFIT2 interferon-induced protein with tetratricopeptide repeats 2 3433 ENSG00000119922
3  ENSG00000059378 NA PARP12 poly (ADP-ribose) polymerase family, member 12 64761 ENSG00000059378
4  ENSG00000133106 NA EPSTI1 epithelial stromal interaction 1 (breast) 94240 ENSG00000133106
5  ENSG00000136040 NA PLXNC1 plexin C1 10154 ENSG00000136040
6  ENSG00000130813 NA C19orf66 chromosome 19 open reading frame 66 55337 ENSG00000130813
7  ENSG00000184979 NA USP18 ubiquitin specific peptidase 18 11274 ENSG00000184979
8  ENSG00000130303 NA BST2 bone marrow stromal cell antigen 2 684 ENSG00000130303
9  ENSG00000160710 NA ADAR adenosine deaminase, RNA-specific 103 ENSG00000160710
10  ENSG00000135114 NA OASL 2'-5'-oligoadenylate synthetase-like 8638 ENSG00000135114
11  ENSG00000137628 NA DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 55601 ENSG00000137628
12  ENSG00000187608 NA ISG15 ISG15 ubiquitin-like modifier 9636 ENSG00000187608
13  ENSG00000132530 NA XAF1 XIAP associated factor 1 54739 ENSG00000132530


Database:Transcription Target       Name:hsa_STTTCRNTTT_V$IRF_Q6       ID:DB_ID:2426
C=186; O=12; E=0.28; R=42.81; rawP=9.54e-17; adjP=1.31e-15
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000107201 NA DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 23586 ENSG00000107201
2  ENSG00000119922 NA IFIT2 interferon-induced protein with tetratricopeptide repeats 2 3433 ENSG00000119922
3  ENSG00000108771 NA DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 79132 ENSG00000108771
4  ENSG00000133106 NA EPSTI1 epithelial stromal interaction 1 (breast) 94240 ENSG00000133106
5  ENSG00000136040 NA PLXNC1 plexin C1 10154 ENSG00000136040
6  ENSG00000130813 NA C19orf66 chromosome 19 open reading frame 66 55337 ENSG00000130813
7  ENSG00000184979 NA USP18 ubiquitin specific peptidase 18 11274 ENSG00000184979
8  ENSG00000137965 NA IFI44 interferon-induced protein 44 10561 ENSG00000137965
9  ENSG00000130303 NA BST2 bone marrow stromal cell antigen 2 684 ENSG00000130303
10  ENSG00000119917 NA IFIT3 interferon-induced protein with tetratricopeptide repeats 3 3437 ENSG00000119917
11  ENSG00000187608 NA ISG15 ISG15 ubiquitin-like modifier 9636 ENSG00000187608
12  ENSG00000132530 NA XAF1 XIAP associated factor 1 54739 ENSG00000132530


Database:Transcription Target       Name:hsa_V$ICSBP_Q6       ID:DB_ID:2210
C=246; O=9; E=0.37; R=24.27; rawP=1.34e-10; adjP=1.47e-09
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000068079 NA IFI35 interferon-induced protein 35 3430 ENSG00000068079
2  ENSG00000160710 NA ADAR adenosine deaminase, RNA-specific 103 ENSG00000160710
3  ENSG00000059378 NA PARP12 poly (ADP-ribose) polymerase family, member 12 64761 ENSG00000059378
4  ENSG00000119917 NA IFIT3 interferon-induced protein with tetratricopeptide repeats 3 3437 ENSG00000119917
5  ENSG00000115267 NA IFIH1 interferon induced with helicase C domain 1 64135 ENSG00000115267
6  ENSG00000184979 NA USP18 ubiquitin specific peptidase 18 11274 ENSG00000184979
7  ENSG00000187608 NA ISG15 ISG15 ubiquitin-like modifier 9636 ENSG00000187608
8  ENSG00000137965 NA IFI44 interferon-induced protein 44 10561 ENSG00000137965
9  ENSG00000130303 NA BST2 bone marrow stromal cell antigen 2 684 ENSG00000130303


Database:Transcription Target       Name:hsa_V$IRF1_01       ID:DB_ID:1880
C=247; O=7; E=0.37; R=18.80; rawP=9.74e-08; adjP=8.93e-07
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000107201 NA DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 23586 ENSG00000107201
2  ENSG00000136040 NA PLXNC1 plexin C1 10154 ENSG00000136040
3  ENSG00000184979 NA USP18 ubiquitin specific peptidase 18 11274 ENSG00000184979
4  ENSG00000132530 NA XAF1 XIAP associated factor 1 54739 ENSG00000132530
5  ENSG00000187608 NA ISG15 ISG15 ubiquitin-like modifier 9636 ENSG00000187608
6  ENSG00000130303 NA BST2 bone marrow stromal cell antigen 2 684 ENSG00000130303
7  ENSG00000213928 NA IRF9 interferon regulatory factor 9 10379 ENSG00000213928


Database:Transcription Target       Name:hsa_V$IRF2_01       ID:DB_ID:1881
C=125; O=5; E=0.19; R=26.54; rawP=1.36e-06; adjP=1.07e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000107201 NA DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 23586 ENSG00000107201
2  ENSG00000136040 NA PLXNC1 plexin C1 10154 ENSG00000136040
3  ENSG00000184979 NA USP18 ubiquitin specific peptidase 18 11274 ENSG00000184979
4  ENSG00000132530 NA XAF1 XIAP associated factor 1 54739 ENSG00000132530
5  ENSG00000130303 NA BST2 bone marrow stromal cell antigen 2 684 ENSG00000130303


Database:Transcription Target       Name:hsa_V$STAT5A_01       ID:DB_ID:2112
C=243; O=3; E=0.37; R=8.19; rawP=0.0060; adjP=0.0367
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000118495 NA PLAGL1 pleiomorphic adenoma gene-like 1 5325 ENSG00000118495
2  ENSG00000104490 NA NCALD neurocalcin delta 83988 ENSG00000104490
3  ENSG00000213928 NA IRF9 interferon regulatory factor 9 10379 ENSG00000213928


Database:Transcription Target       Name:hsa_V$STAT5B_01       ID:DB_ID:2113
C=239; O=3; E=0.36; R=8.33; rawP=0.0057; adjP=0.0367
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000118495 NA PLAGL1 pleiomorphic adenoma gene-like 1 5325 ENSG00000118495
2  ENSG00000104490 NA NCALD neurocalcin delta 83988 ENSG00000104490
3  ENSG00000213928 NA IRF9 interferon regulatory factor 9 10379 ENSG00000213928


Database:Transcription Target       Name:hsa_V$HSF1_01       ID:DB_ID:1949
C=265; O=3; E=0.40; R=7.51; rawP=0.0076; adjP=0.0418
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000168175 NA MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like 93487 ENSG00000168175
2  ENSG00000136040 NA PLXNC1 plexin C1 10154 ENSG00000136040
3  ENSG00000002549 NA LAP3 leucine aminopeptidase 3 51056 ENSG00000002549




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).